Pseudomonas aeruginosa transition Mini-Review

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La bacteria oportunista Pseudomonas aeruginosa es una de las principales preocupaciones como agente etiológico de infecciones nosocomiales en humanos. Muchos de los factores de virulencia utilizados para colonizar el cuerpo humano son los mismos que utiliza P. aeruginosa para prosperar en el medio ambiente, como el transporte por membrana, la formación de biopelículas y la reacción de oxidación/reducción, entre otros. El origen de P. aeruginosa es principalmente el medio ambiente, la adaptación a los tejidos de los mamíferos puede seguir un modelo de evolución fuente-sumidero; el medio ambiente es la fuente de muchos linajes, algunos de ellos capaces de adaptarse al cuerpo humano. Algunos linajes pueden adaptarse a los humanos y pasar por una evolución reductora en la que se pierden algunos genes.  La comprensión de este proceso puede ser fundamental para aplicar mejores métodos de control de brotes en los hospitales.

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Vasco, G., & Gabriel Trueba. (2021). Pseudomonas aeruginosa transition: Mini-Review. ACI Avances En Ciencias E Ingenierías, 13(1), 11. https://doi.org/10.18272/aci.v13i1.2225
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SECCIÓN B: CIENCIAS BIOLÓGICAS Y AMBIENTALES

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[1] Juan, C., Peña, C., & Oliver, A. (2017). Host and Pathogen Biomarkers for Severe Pseudomonas aeruginosa Infections. The Journal of Infectious Diseases, 215(suppl_1), S44-S51. https://doi.org/10.1093/infdis/jiw299

[2] Ding, C., Yang, Z., Wang, J., Liu, X., Cao, Y., Pan, Y., Han, L., & Zhan, S. (2016). Prevalence of Pseudomonas aeruginosa and antimicrobial-resistant Pseudomonas aeruginosa in patients with pneumonia in mainland China: A systematic review and meta-analysis. International Journal of Infectious Diseases, 49, 119-128. https://doi.org/10.1016/j.ijid.2016.06.014

[3] Ribeiro, Á. C. da S., Crozatti, M. T. L., Silva, A. A. da, Macedo, R. S., Machado, A. M. de O., & Silva, A. T. de A. (2020). Pseudomonas aeruginosa in the ICU: Prevalence, resistance profile, and antimicrobial consumption. Revista da Sociedade Brasileira de Medicina Tropical, 53, e20180498. https://doi.org/10.1590/0037-8682-0498-2018

[4] Monsó, E. (2017). Microbiome in chronic obstructive pulmonary disease. Annals of Translational Medicine, 5(12), 251-251. https://doi.org/10.21037/atm.2017.04.20

[5] Rodrigo-Troyano, A., & Sibila, O. (2017). The respiratory threat posed by multidrug resistant Gram-negative bacteria: MDR-GNB in respiratory infections. Respirology, 22(7), 1288-1299. https://doi.org/10.1111/resp.13115

[6] Teweldemedhin, M., Gebreyesus, H., Atsbaha, A. H., Asgedom, S. W., & Saravanan, M. (2017). Bacterial profile of ocular infections: A systematic review. BMC Ophthalmology, 17(1). https://doi.org/10.1186/s12886-017-0612-2

[7] Roser, D. J., Van Den Akker, B., Boase, S., Haas, C. N., Ashbolt, N. J., & Rice, S. A. (2014). Pseudomonas aeruginosa dose response and bathing water infection. Epidemiology and Infection, 142(03), 449-462. https://doi.org/10.1017/S0950268813002690

[8] Moremi, N., Claus, H., Vogel, U., & Mshana, S. E. (2017). Surveillance of surgical site infections by Pseudomonas aeruginosa and strain characterization in Tanzanian hospitals does not provide proof for a role of hospital water plumbing systems in transmission. Antimicrobial Resistance & Infection Control, 6(1). https://doi.org/10.1186/s13756-017-0216-x

[9] De Soyza, A., & Winstanley, C. (2018). Pseudomonas aeruginosa and Bronchiectasis. En J. Chalmers, E. Polverino, & S. Aliberti (Eds.), Bronchiectasis (pp. 157-180). Springer International Publishing. https://doi.org/10.1007/978-3-319-61452-6_12

[10] Engelhart, S., Krizek, L., Glasmacher, A., Fischnaller, E., Marklein, G., & Exner, M. (2002). Pseudomonas aeruginosa outbreak in a haematology–oncology unit associated with contaminated surface cleaning equipment. Journal of Hospital Infection, 52(2), 93-98. https://doi.org/10.1053/jhin.2002.1279

[11] English, E. L., Schutz, K. C., Willsey, G. G., & Wargo, M. J. (2018). Transcriptional Responses of Pseudomonas aeruginosa to Potable Water and Freshwater. Applied and Environmental Microbiology, 84(6). https://doi.org/10.1128/AEM.02350-17

[12] Hahn, M. W., & Höfle, M. G. (2001). Grazing of protozoa and its effect on populations of aquatic bacteria. FEMS Microbiology Ecology, 35(2), 113-121. https://doi.org/10.1111/j.1574-6941.2001.tb00794.x

[13] Abalos, A., Viñas, M., Sabaté, J., Manresa, M. A., & Solanas, A. M. (2004). Enhanced Biodegradation of Casablanca Crude Oil by A Microbial Consortium in Presence of a Rhamnolipid Produced by Pseudomonas aeruginosa AT10. Biodegradation, 15(4), 249-260. https://doi.org/10.1023/B:BIOD.0000042915.28757.fb

[14] Benie, C. K. D., Dadié, A., Guessennd, N., N’gbesso-Kouadio, N. A., Kouame, N. D., N’golo, D. C., Aka, S., Dako, E., Dje, K. M., & Dosso, M. (2017). Characterization of virulence potential of Pseudomonas aeruginosa isolated from bovine meat, fresh fish, and smoked fish. European Journal of Microbiology and Immunology, 7(1), 55-64. https://doi.org/10.1556/1886.2016.00039

[15] Das, K., & Mukherjee, A. K. (2007). Crude petroleum-oil biodegradation efficiency of Bacillus subtilis and Pseudomonas aeruginosa strains isolated from a petroleum-oil contaminated soil from North-East India. Bioresource Technology, 98(7), 1339-1345. https://doi.org/10.1016/j.biortech.2006.05.032

[16] Gupta, B., Kunal, Rajor, A., & Kaur, J. (2018). Isolation, Characterisation of Novel Pseudomonas and Enterobacter sp. From Contaminated Soil of Chandigarh for Naphthalene Degradation. En S. K. Ghosh (Ed.), Utilization and Management of Bioresources (pp. 175-186). Springer Singapore. https://doi.org/10.1007/978-981-10-5349-8_17

[17] Kotresha, D., & Vidyasagar, G. M. (2008). Isolation and characterisation of phenol-degrading Pseudomonas aeruginosa MTCC 4996. World Journal of Microbiology and Biotechnology, 24(4), 541-547. https://doi.org/10.1007/s11274-007-9508-2

[18] Tortell, P. D., Maldonado, M. T., & Price, N. M. (1996). The role of heterotrophic bacteria in iron-limited ocean ecosystems. Nature, 383(6598), 330-332. https://doi.org/10.1038/383330a0

[19] Wei, Y.-H., Chou, C.-L., & Chang, J.-S. (2005). Rhamnolipid production by indigenous Pseudomonas aeruginosa J4 originating from petrochemical wastewater. Biochemical Engineering Journal, 27(2), 146-154. https://doi.org/10.1016/j.bej.2005.08.028

[20] Bert, F., Maubec, E., Bruneau, B., Berry, P., & Lambert-Zechovsky, N. (1998). Multi-resistant Pseudomonas aeruginosa outbreak associated with contaminated tap water in a neurosurgery intensive care unit. Journal of Hospital Infection, 39(1), 53-62. https://doi.org/10.1016/S0195-6701(98)90243-2

[21] Meyer, B. (2003). Approaches to prevention, removal and killing of biofilms. International Biodeterioration & Biodegradation, 51(4), 249-253. https://doi.org/10.1016/S0964-8305(03)00047-7

[22] Chatterjee, M., Anju, C., Biswas, L., Anil Kumar, V., Gopi Mohan, C., & Biswas, R. (2016). Antibiotic resistance in Pseudomonas aeruginosa and alternative therapeutic options. International Journal of Medical Microbiology: IJMM, 306(1), 48-58. https://doi.org/10.1016/j.ijmm.2015.11.004

[23] Ruiz-Garbajosa, P., & Cantón, R. (2017). Epidemiology of antibiotic resistance in Pseudomonas aeruginosa. Implications for empiric and definitive therapy. Revista Espanola De Quimioterapia: Publicacion Oficial De La Sociedad Espanola De Quimioterapia, 30 Suppl 1, 8-12.

[24] Subedi, D., Vijay, A. K., & Willcox, M. (2018). Overview of mechanisms of antibiotic resistance in Pseudomonas aeruginosa: An ocular perspective: Mechanism of antimicrobial resistance in P. aeruginosa. Clinical and Experimental Optometry, 101(2), 162-171. https://doi.org/10.1111/cxo.12621

[25] Sokurenko, E. V., Gomulkiewicz, R., & Dykhuizen, D. E. (2006). Source–sink dynamics of virulence evolution. Nature Reviews Microbiology, 4(7), 548-555. https://doi.org/10.1038/nrmicro1446

[26] Dettman, J. R., Rodrigue, N., Aaron, S. D., & Kassen, R. (2013). Evolutionary genomics of epidemic and nonepidemic strains of Pseudomonas aeruginosa. Proceedings of the National Academy of Sciences, 110(52), 21065-21070. https://doi.org/10.1073/pnas.1307862110

[27] Dettman, Jeremy R., Rodrigue, N., & Kassen, R. (2015). Genome-Wide Patterns of Recombination in the Opportunistic Human Pathogen Pseudomonas aeruginosa. Genome Biology and Evolution, 7(1), 18-34. https://doi.org/10.1093/gbe/evu260

[28] Pukatzki, S., Kessin, R. H., & Mekalanos, J. J. (2002). The human pathogen Pseudomonas aeruginosa utilizes conserved virulence pathways to infect the social amoeba Dictyostelium discoideum. Proceedings of the National Academy of Sciences of the United States of America, 99(5), 3159-3164. https://doi.org/10.1073/pnas.052704399

[29] Wolfgang, M. C., Kulasekara, B. R., Liang, X., Boyd, D., Wu, K., Yang, Q., Miyada, C. G., & Lory, S. (2003). Conservation of genome content and virulence determinants among clinical and environmental isolates of Pseudomonas aeruginosa. Proceedings of the National Academy of Sciences, 100(14), 8484-8489. https://doi.org/10.1073/pnas.0832438100

[30] Abd, H., Wretlind, B., Saeed, A., Idsund, E., Hultenby, K., & Sandstrã–M, G. (2008). Pseudomonas aeruginosa Utilises Its Type III Secretion System to Kill the Free-Living Amoeba Acanthamoeba castellanii. Journal of Eukaryotic Microbiology, 55(3), 235-243. https://doi.org/10.1111/j.1550-7408.2008.00311.x

[31] Matz, C., Moreno, A. M., Alhede, M., Manefield, M., Hauser, A. R., Givskov, M., & Kjelleberg, S. (2008). Pseudomonas aeruginosa uses type III secretion system to kill biofilm-associated amoebae. The ISME Journal, 2(8), 843-852. https://doi.org/10.1038/ismej.2008.47

[32] Hauser, A. R. (2009). The type III secretion system of Pseudomonas aeruginosa: Infection by injection. Nature Reviews Microbiology, 7(9), 654-665. https://doi.org/10.1038/nrmicro2199

[33] Epelman, S., Stack, D., Bell, C., Wong, E., Neely, G. G., Krutzik, S., Miyake, K., Kubes, P., Zbytnuik, L. D., Ma, L. L., Xie, X., Woods, D. E., & Mody, C. H. (2004). Different Domains of Pseudomonas aeruginosa Exoenzyme S Activate Distinct TLRs. The Journal of Immunology, 173(3), 2031-2040. https://doi.org/10.4049/jimmunol.173.3.2031

[34] Teitzel, G. M., Geddie, A., De Long, S. K., Kirisits, M. J., Whiteley, M., & Parsek, M. R. (2006). Survival and Growth in the Presence of Elevated Copper: Transcriptional Profiling of Copper-Stressed Pseudomonas aeruginosa. Journal of Bacteriology, 188(20), 7242-7256. https://doi.org/10.1128/JB.00837-06

[35] Schalk, I. J., & Guillon, L. (2013). Pyoverdine biosynthesis and secretion in Pseudomonas aeruginosa: Implications for metal homeostasis: Pyoverdine biosynthesis. Environmental Microbiology, 15(6), 1661-1673. https://doi.org/10.1111/1462-2920.12013

[36] Meyer, J. M., Neely, A., Stintzi, A., Georges, C., & Holder, I. A. (1996). Pyoverdin is essential for virulence of Pseudomonas aeruginosa. Infection and Immunity, 64(2), 518-523.

[37] Touati, D. (2000). Iron and Oxidative Stress in Bacteria. Archives of Biochemistry and Biophysics, 373(1), 1-6. https://doi.org/10.1006/abbi.1999.1518

[38] Silby, M. W., Winstanley, C., Godfrey, S. A. C., Levy, S. B., & Jackson, R. W. (2011). Pseudomonas genomes: Diverse and adaptable. FEMS Microbiology Reviews, 35(4), 652-680. https://doi.org/10.1111/j.1574-6976.2011.00269.x

[39] Pirnay, J.-P., Bilocq, F., Pot, B., Cornelis, P., Zizi, M., Van Eldere, J., Deschaght, P., Vaneechoutte, M., Jennes, S., Pitt, T., & De Vos, D. (2009). Pseudomonas aeruginosa Population Structure Revisited. PLoS ONE, 4(11), e7740. https://doi.org/10.1371/journal.pone.0007740

[40] Parcell, B. J., Oravcova, K., Pinheiro, M., Holden, M. T. G., Phillips, G., Turton, J. F., & Gillespie, S. H. (2018). Pseudomonas aeruginosa intensive care unit outbreak: Winnowing of transmissions with molecular and genomic typing. Journal of Hospital Infection, 98(3), 282-288. https://doi.org/10.1016/j.jhin.2017.12.005

[41] Quick, J., Cumley, N., Wearn, C. M., Niebel, M., Constantinidou, C., Thomas, C. M., Pallen, M. J., Moiemen, N. S., Bamford, A., Oppenheim, B., & Loman, N. J. (2014). Seeking the source of Pseudomonas aeruginosa infections in a recently opened hospital: An observational study using whole-genome sequencing. BMJ Open, 4(11), e006278. https://doi.org/10.1136/bmjopen-2014-006278

[42] Sánchez, D., Gomila, M., Bennasar, A., Lalucat, J., & García-Valdés, E. (2014). Genome Analysis of Environmental and Clinical Pseudomonas aeruginosa Isolates from Sequence Type-1146. PLoS ONE, 9(10), e107754. https://doi.org/10.1371/journal.pone.0107754

[43] Lucchetti-Miganeh, C., Redelberger, D., Chambonnier, G., Rechenmann, F., Elsen, S., Bordi, C., Jeannot, K., Attrée, I., Plésiat, P., & de Bentzmann, S. (2014). Pseudomonas aeruginosa Genome Evolution in Patients and under the Hospital Environment. Pathogens, 3(2), 309-340. https://doi.org/10.3390/pathogens3020309

[44] Mahenthiralingam, E., Campbell, M. E., & Speert, D. P. (1994). Nonmotility and phagocytic resistance of Pseudomonas aeruginosa isolates from chronically colonized patients with cystic fibrosis. Infection and Immunity, 62(2), 596-605.

[45] Diaz Caballero, J., Clark, S. T., Coburn, B., Zhang, Y., Wang, P. W., Donaldson, S. L., Tullis, D. E., Yau, Y. C. W., Waters, V. J., Hwang, D. M., & Guttman, D. S. (2015). Selective Sweeps and Parallel Pathoadaptation Drive Pseudomonas aeruginosa Evolution in the Cystic Fibrosis Lung. MBio, 6(5). https://doi.org/10.1128/mBio.00981-15

[46] Tamburini, F. B., Andermann, T. M., Tkachenko, E., Senchyna, F., Banaei, N., & Bhatt, A. S. (2018). Precision identification of diverse bloodstream pathogens in the gut microbiome. Nature Medicine, 24(12), 1809-1814. https://doi.org/10.1038/s41591-018-0202-8

[47] Cholley, P., Thouverez, M., Hocquet, D., van der Mee-Marquet, N., Talon, D., & Bertrand, X. (2011). Most Multidrug-Resistant Pseudomonas aeruginosa Isolates from Hospitals in Eastern France Belong to a Few Clonal Types. Journal of Clinical Microbiology, 49(7), 2578-2583. https://doi.org/10.1128/JCM.00102-11

[48] Bhagirath, A. Y., Li, Y., Somayajula, D., Dadashi, M., Badr, S., & Duan, K. (2016). Cystic fibrosis lung environment and Pseudomonas aeruginosa infection. BMC Pulmonary Medicine, 16(1). https://doi.org/10.1186/s12890-016-0339-5

[49] Williams, B. J., Dehnbostel, J., & Blackwell, T. S. (2010). Pseudomonas aeruginosa: Host defense in lung diseases. Respirology, 15(7), 1037-1056. https://doi.org/10.1111/j.1440-1843.2010.01819.x

[50] Perron, G. G., Gonzalez, A., & Buckling, A. (2007). Source-sink dynamics shape the evolution of antibiotic resistance and its pleiotropic fitness cost. Proceedings of the Royal Society B: Biological Sciences, 274(1623), 2351-2356. https://doi.org/10.1098/rspb.2007.0640

[51] Holt, R. D., Barfield, M., & Gomulkiewicz, R. (2004). Temporal Variation Can Facilitate Niche Evolution in Harsh Sink Environments. The American Naturalist, 164(2), 187-200. https://doi.org/10.1086/422343

[52] Kassen, R. (2002). The experimental evolution of specialists, generalists, and the maintenance of diversity: Experimental evolution in variable environments. Journal of Evolutionary Biology, 15(2), 173-190. https://doi.org/10.1046/j.1420-9101.2002.00377.x

[53] Juárez-Vázquez, A. L., Edirisinghe, J. N., Verduzco-Castro, E. A., Michalska, K., Wu, C., Noda-García, L., Babnigg, G., Endres, M., Medina-Ruíz, S., Santoyo-Flores, J., Carrillo-Tripp, M., Ton-That, H., Joachimiak, A., Henry, C. S., & Barona-Gómez, F. (2017). Evolution of substrate specificity in a retained enzyme driven by gene loss. ELife, 6. https://doi.org/10.7554/eLife.22679

[54] Zhang, X., Liu, X., Liang, Y., Guo, X., Xiao, Y., Ma, L., Miao, B., Liu, H., Peng, D., Huang, W., Zhang, Y., & Yin, H. (2017). Adaptive Evolution of Extreme Acidophile Sulfobacillus thermosulfidooxidans Potentially Driven by Horizontal Gene Transfer and Gene Loss. Applied and Environmental Microbiology, 83(7). https://doi.org/10.1128/AEM.03098-16

[55] Moran, N. A. (2002). Microbial minimalism: Genome reduction in bacterial pathogens. Cell, 108(5), 583-586.

[56] Andersen, S. B., Ghoul, M., Griffin, A. S., Petersen, B., Johansen, H. K., & Molin, S. (2017). Diversity, Prevalence, and Longitudinal Occurrence of Type II Toxin-Antitoxin Systems of Pseudomonas aeruginosa Infecting Cystic Fibrosis Lungs. Frontiers in Microbiology, 8. https://doi.org/10.3389/fmicb.2017.01180

[57] Barth, A. L., & Pitt, T. L. (1996). The high amino-acid content of sputum from cystic fibrosis patients promotes growth of auxotrophic Pseudomonas aeruginosa. Journal of Medical Microbiology, 45(2), 110-119. https://doi.org/10.1099/00222615-45-2-110

[58] Thomas, S. R. (2000). Increased sputum amino acid concentrations and auxotrophy of Pseudomonas aeruginosa in severe cystic fibrosis lung disease. Thorax, 55(9), 795-797. https://doi.org/10.1136/thorax.55.9.795

[59] Huse, H. K., Kwon, T., Zlosnik, J. E. A., Speert, D. P., Marcotte, E. M., & Whiteley, M. (2010). Parallel Evolution in Pseudomonas aeruginosa over 39,000 Generations In Vivo. MBio, 1(4). https://doi.org/10.1128/mBio.00199-10

[60] Nguyen, A. T., O’Neill, M. J., Watts, A. M., Robson, C. L., Lamont, I. L., Wilks, A., & Oglesby-Sherrouse, A. G. (2014). Adaptation of Iron Homeostasis Pathways by a Pseudomonas aeruginosa Pyoverdine Mutant in the Cystic Fibrosis Lung. Journal of Bacteriology, 196(12), 2265-2276. https://doi.org/10.1128/JB.01491-14

[61] Ghio, A. J., Roggli, V. L., Soukup, J. M., Richards, J. H., Randell, S. H., & Muhlebach, M. S. (2013). Iron accumulates in the lavage and explanted lungs of cystic fibrosis patients. Journal of Cystic Fibrosis, 12(4), 390-398. https://doi.org/10.1016/j.jcf.2012.10.010

[62] Wegiel, B., Nemeth, Z., Correa-Costa, M., Bulmer, A. C., & Otterbein, L. E. (2014). Heme Oxygenase-1: A Metabolic Nike. Antioxidants & Redox Signaling, 20(11), 1709-1722. https://doi.org/10.1089/ars.2013.5667

[63] Huse, H. K., Kwon, T., Zlosnik, J. E. A., Speert, D. P., Marcotte, E. M., & Whiteley, M. (2013). Pseudomonas aeruginosa Enhances Production of a Non-Alginate Exopolysaccharide during Long-Term Colonization of the Cystic Fibrosis Lung. PLoS ONE, 8(12), e82621. https://doi.org/10.1371/journal.pone.0082621

[64] Smith, E. E., Buckley, D. G., Wu, Z., Saenphimmachak, C., Hoffman, L. R., D’Argenio, D. A., Miller, S. I., Ramsey, B. W., Speert, D. P., Moskowitz, S. M., Burns, J. L., Kaul, R., & Olson, M. V. (2006). Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients. Proceedings of the National Academy of Sciences, 103(22), 8487-8492. https://doi.org/10.1073/pnas.0602138103

[65] Oliver, A., Cantón, R., Campo, P., Baquero, F., & Blázquez, J. (2000). High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection. Science (New York, N.Y.), 288(5469), 1251-1254

[66] Mena, A., Smith, E. E., Burns, J. L., Speert, D. P., Moskowitz, S. M., Perez, J. L., & Oliver, A. (2008). Genetic Adaptation of Pseudomonas aeruginosa to the Airways of Cystic Fibrosis Patients Is Catalyzed by Hypermutation. Journal of Bacteriology, 190(24), 7910-7917. https://doi.org/10.1128/JB.01147-08

[67] Lam, J., Chan, R., Lam, K., & Costerton, J. W. (1980). Production of mucoid microcolonies by Pseudomonas aeruginosa within infected lungs in cystic fibrosis. Infection and Immunity, 28(2), 546-556.

[68] Sriramulu, D. D. (2005). Microcolony formation: A novel biofilm model of Pseudomonas aeruginosa for the cystic fibrosis lung. Journal of Medical Microbiology, 54(7), 667-676. https://doi.org/10.1099/jmm.0.45969-0

[69] Treepong, P., Kos, V. N., Guyeux, C., Blanc, D. S., Bertrand, X., Valot, B., & Hocquet, D. (2018). Global emergence of the widespread Pseudomonas aeruginosa ST235 clone. Clinical Microbiology and Infection, 24(3), 258-266. https://doi.org/10.1016/j.cmi.2017.06.018

[70] Yang, L., Jelsbak, L., Marvig, R. L., Damkiaer, S., Workman, C. T., Rau, M. H., Hansen, S. K., Folkesson, A., Johansen, H. K., Ciofu, O., Hoiby, N., Sommer, M. O. A., & Molin, S. (2011). Evolutionary dynamics of bacteria in a human host environment. Proceedings of the National Academy of Sciences, 108(18), 7481-7486. https://doi.org/10.1073/pnas.1018249108

[71] Kawecki, T. J., & Ebert, D. (2004). Conceptual issues in local adaptation. Ecology Letters, 7(12), 1225-1241. https://doi.org/10.1111/j.1461-0248.2004.00684.x

[72] Chatterjee, P., Davis, E., Yu, F., James, S., Wildschutte, J. H., Wiegmann, D. D., Sherman, D. H., McKay, R. M., LiPuma, J. J., & Wildschutte, H. (2017). Environmental Pseudomonads Inhibit Cystic Fibrosis Patient-Derived Pseudomonas aeruginosa. Applied and Environmental Microbiology, 83(2). https://doi.org/10.1128/AEM.02701-16