The real origin of the COVID-19 Pandemic
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Keywords

COVID-19
pandemic
virus origin
public health
misinformation

How to Cite

Trueba, G. (2025). The real origin of the COVID-19 Pandemic. ACI Avances En Ciencias E Ingenierías, 17(2). https://doi.org/10.18272/aci.3892

Abstract

In December 2019, an outbreak of pneumonia in Wuhan marked the epicenter of the COVID-19 pandemic. Although a novel coronavirus similar to the SARS virus responsible for an epidemic in 2002 was identified, two hypotheses emerged regarding its origin: the live animal market in Wuhan or a potential leak from the Wuhan Institute of Virology (WIV). Most scientific experts support the hypothesis of a natural origin and transmission from the live animal market. However, certain political groups in the United States promoted the lab-leak theory, which undermined trust in scientific communication. One consequence of this mistrust in science was resistance to public health measures such as vaccination, mask-wearing, and social distancing, along with growing skepticism toward scientific activity. These dynamics have serious implications for public health and for future virus surveillance efforts. 

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References

Hegarty, S. (6, February 2020). The Chinese doctor who tried to warn others about coronavirus. BBC News. https://www.bbc.com/news/world-asia-china-51364382

Xu, R. H., He, J. F., Evans, M. R., Peng, G. W., Field, H. E., Yu, D. W., Lee, C. K., Luo, H. M., Lin, W. S., Lin, P., Li, L. H., Liang, W. J., Lin, J. Y., & Schnur, A. (2004). Epidemiologic clues to SARS origin in China. Emerging Infectious Diseases, 10(6), 1030–1037. https://doi.org/10.3201/eid1006.030852

Standaert, M. (25, February 2020). Coronavirus closures reveal vast scale of China’s secretive wildlife farm industry. The Guardian. https://www.theguardian.com/environment/2020/feb/25/coronavirus-closures-reveal-vast-scale-of-chinas-secretive-wildlife-farm-industry

Crits-Christoph, A., Levy, J. I., Pekar, J. E., Goldstein, S. A., Singh, R., Hensel, Z., Gangavarapu, K., Rogers, M. B., Moshiri, N., Garry, R. F., Holmes, E. C., Koopmans, M. P. G., Lemey, P., Peacock, T. P., Popescu, S., Rambaut, A., Robertson, D. L., Suchard, M. A., Wertheim, J. O., … & Débarre, F. (2024). Genetic tracing of market wildlife and viruses at the epicenter of the COVID-19 pandemic. Cell, 187(19), 5468–5482. https://doi.org/10.1016/j.cell.2024.09.020

Mallapaty, S. (2024). Wuhan lab samples hold no close relatives to the virus behind COVID. Nature, 636(8043), 531–532. https://doi.org/10.1038/d41586-024-03982-2

Hu, B., Zeng, L. P., Yang, X. L., Ge, X. Y., Zhang, W., Li, B., Xie, J. Z., Shen, X. R., Zhang, Y. Z., Wang, N., Luo, D. S., Zheng, X. S., Wang, M. N., Daszak, P., Wang, L. F., Cui, J., & Shi, Z. L. (2017). Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus. PLoS Pathogens, 13(11), e1006698. https://doi.org/10.1371/journal.ppat.1006698

Mallapaty, S. (2025). What sparked the COVID pandemic? Mounting evidence points to raccoon dogs. Nature, 639(8053), 14–15. https://doi.org/10.1038/d41586-025-00426-3

Worobey, M., Levy, J. I., Malpica Serrano, L., Crits-Christoph, A., Pekar, J. E., Goldstein, S. A., Rasmussen, A. L., Kraemer, M. U. G., Newman, C., Koopmans, M. P. G., Suchard, M. A., Wertheim, J. O., Lemey, P., Robertson, D. L., Garry, R. F., Holmes, E. C., Rambaut, A., & Andersen, K. G. (2022). The Huanan seafood wholesale market in Wuhan was the early epicenter of the COVID-19 pandemic. Science, 377(6609), 951–959. https://doi.org/10.1126/science.abp8715

Cortez, M. F. (2021, June 27). The last—and only—foreign scientist in the Wuhan lab speaks out. Bloomberg. https://www.bloomberg.com/news/features/2021-06-27/did-covid-come-from-a-lab-scientist-at-wuhan-institute-speaks-out

Menachery, V. D., Yount, B. L., Jr., Debbink, K., Agnihothram, S., Gralinski, L. E., Plante, J. A., Graham, R. L., Scobey, T., Ge, X. Y., Donaldson, E. F., Randell, S. H., Lanzavecchia, A., Marasco, W. A., Shi, Z. L., & Baric, R. S. (2015). A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nature Medicine, 21(12), 1508–1513. https://doi.org/10.1038/nm.3985

Vilches, T. N., Moghadas, S. M., Sah, P., Fitzpatrick, M. C., Shoukat, A., Pandey, A., & Galvani, A. P. (2022). Estimating COVID-19 infections, hospitalizations, and deaths following the US vaccination campaigns during the pandemic. JAMA Network Open, 5(1). https://doi.org/10.1001/jamanetworkopen.2021.42725

O’Grady, C. (2022, September 15). In the line of fire: Scientists have been harassed for years. But a Science survey shows the pandemic has made things far worse for some. Science. https://www.science.org/content/article/overwhelmed-hate-covid-19-scientists-face-avalanche-abuse-survey-shows

Kuhn, T. S. (1962). The structure of scientific revolutions. University of Chicago Press.

Enserink, M. (2024, March 20). Virologists and epidemiologists back natural origin for COVID-19, survey suggests. Science. https://www.science.org/content/article/virologists-and-epidemiologists-back-natural-origin-covid-19-survey-suggests

Poonia, G. (2024, April 17). 7 out of 10 American voters think COVID-19 came from a lab. Deseret News. https://www.deseret.com/politics/2024/04/17/what-are-the-origins-of-covid-19/

Nava, V. (2025, January 18). HHS bans EcoHealth Alliance and group’s ex-prez from receiving federal funding for 5 years after Wuhan virus experiments. New York Post. https://nypost.com/2025/01/18/us-news/hhs-bans-ecohealth-alliance-and-groups-ex-prez-from-receiving-federal-funding-for-5-years-after-wuhan-virus-experiments/

Temmam, S., Vongphayloth, K., Baquero, E., Munier, S., Bonomi, M., Regnault, B., Douangboubpha, B., Karami, Y., Chrétien, D., Sanamxay, D., Xayaphet, V., Paphaphanh, P., Lacoste, V., Somlor, S., Lakeomany, K., Phommavanh, N., Pérot, P., Dehan, O., Amara, F., …, &+ Eloit, M. (2022). Bat coronaviruses related to SARS-CoV-2 and infectious for human cells. Nature, 604(7905), 330–336. https://doi.org/10.1038/s41586-022-04532-4

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Copyright (c) 2025 Gabriel Trueba