Manejo diagnóstico y quirúrgico del Granuloma Central de Células gigantes. A propósito de un caso clínico.
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Published:
Feb 25, 2021
Section
Casos Clínicos Cirugía
Main Article Content
Abstract
The central giant cell granuloma is a benign, intraosseous and osteolytic lesion of non-odontogenic origin, with no reports published so far that can become a malignant pathology. We presented a case of a 69-years-old male patient who presented intraoral volume increase on the left side, evolution time was not quantified, non-painful, prevented the placement of his dental prosthesis. Image studies and stereolithographic models were performed and demonstrate the presence of a wide lithic zone located below the piriform aperture. Cystic mass enucleation, aggressive curettage of bony walls and cleaning of surgical field with chemical solution was done. The objective of this study is to provide the necessary guidelines for the diagnosis of central giant cell granuloma in order to carry out an adequate treatment without risk of recurrence.
Keywords:
Granuloma, Giant cell,, Treatment,, Maxillary, Surgical curettage, Recurrence rate,
Article Details
How to Cite
Criollo, A., & Unda, P. (2021). Manejo diagnóstico y quirúrgico del Granuloma Central de Células gigantes. A propósito de un caso clínico. OdontoInvestigación, 7(1), 4–13. https://doi.org/10.18272/oi.v7i1.1890
References
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Kudva A, Cariappa K, Dhara V, Solomon M. Central giant cell granuloma: An uncommon presentation. Oral and Maxillofacial Surgery Cases. 2018;4(4):135-140.
Bocchialini G, Salvagni L, Guerini A, Castellani A. Central giant cell granuloma of the mandibular condyle: A rare case and a literature review. 2020;6(1):1-4.
Garg P, Jain J, De N, Chatterjee K. A central giant cell granuloma in posterior part of maxilla"”A case report. International Journal of Surgery Case Reports. 2017;30:222-225.
Yamaguchi T, Dorfman D. Giant cell reparative granuloma: a comparative clinicopathologic study of lesions in gnathic and extragnathic sites. Int J Surg Pathol. 2001;9(3):189- 200
Kermer C, Millesi W, Watzke M. Local injection of corticosteroids for central giant cell granuloma. A case report, Int J Oral Maxillofac Surg. 1994;23:366-368.
Dickerman JD. Interferon and giant cell tumors, Pediatrics. 1994;103:1282-1283.
Hameed M, O"™Connell J, Rogers S. Management of an aggressive giant cell granuloma of the mandible with denosumab: a case report. British Journal of Oral and Maxillofacial Surgery. 2019;57(7):691-693.
Liu B, Yu S, Li. Multinucleated giant cells in various forms of giant cell containing lesions of the jaws express features of osteoclasts. Journal of Oral Pathology and Medicine. 2003;32(6):367-375.
Chuong R, Kaban L, Kozakewich H, Perez-Atayde A. Central giant cell lesions of the jaws: A clinicopathologic study. Journal of Oral and Maxillofacial Surgery. 1986;44(9):708-713.
Chrcanovic B, Gomes C, Gomez R. Peripheral giant cell granuloma: An updated analysis of 2824 cases reported in the literature. Journal of Oral Pathology & Medicine. 2018;47(5):454-459.
Tabrizi R, Fardisi S, Zamiri B, Amanpour S, Karagah T. Can calcitonin nasal spray reduce the risk of recurrence of central giant cell granuloma of the jaws? A double-blind clinical trial. International Journal of Oral and Maxillofacial Surgery. 2016;45(6):756-759
Carlos R, Sedano H.. Intralesional corticosteroids as an alternative treatment for central giant cell granuloma. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2002;93(2):161-166.
Stavropoulos F, Katz J. Central giant cell granulomas: a systematic review of the radiographic characteristics with the addition of 20 new cases. Dentomaxillofacial Radiology. 2002;31(4):213-217.
Naidu A, Malmquist M, Denham C, Schow. Management of Central Giant Cell Granuloma With Subcutaneous Denosumab Therapy. Journal of Oral and Maxillofacial Surgery. 2014;72(12):2469-2484.
Bredell M, Rordorf T, Kroiss S, Rücker M, Zweifel D, Rostetter C. Denosumab as a Treatment Alternative for Central Giant Cell Granuloma: A Long-Term Retrospective Cohort Study. Journal of Oral and Maxillofacial Surgery. 2018;76(4):775-784.
Mukaihara K, Suehara Y, Kohsaka S, Akaike K, Tanabe Y, Kubota D, Saito T. Protein Expression Profiling of Giant Cell Tumors of Bone Treated with Denosumab. 2016;11(2).
Schreuder W, vandenBerg H, Westermann A, Peacock Z, Lange J. Pharmacological and surgical therapy for the central giant cell granuloma: A long-term retrospective cohort study. Journal of Cranio-Maxillofacial Surgery. 2017;45(2):232-243.
Chen Y, Zhang J, Han Y, Troulis M, August M. Benign Pediatric Jaw Lesions at Massachusetts General Hospital Over 13 Years. Journal of Oral and Maxillofacial Surgery. 2020;78(7):1124-1135.
Angelini A, Pagliarini E, Belluzzi E, Cappellesso R, Ruggieri P. Giant cell reparative granuloma of the scapula: report of a case and literature review. Skeletal Radiol. 2019;48(8):1293-1298.
Atarbashi-Moghadam F, Atarbashi-Moghadam S, Namdari M, Shahrabi-Farahani S. Reactive oral lesions associated with dental implants. A systematic review. J Investig Clin Dent. 2018;9(4).
Gadicherla S, Smriti K, John E, Pentapati K-C, Bhagania M. Intra-lesional medicaments for the management of intra-osseous lesions of maxilla and mandible - systematic review. J Int Soc Prev Community Dent. 2020;10(1):36-45.
Pogrel MA. The Central Giant Cell Granuloma. Current Therapy In Oral and Maxillofacial Surgery. 2012:410-413.
Kudva A, Cariappa K, Dhara V, Solomon M. Central giant cell granuloma: An uncommon presentation. Oral and Maxillofacial Surgery Cases. 2018;4(4):135-140.
Bocchialini G, Salvagni L, Guerini A, Castellani A. Central giant cell granuloma of the mandibular condyle: A rare case and a literature review. 2020;6(1):1-4.
Garg P, Jain J, De N, Chatterjee K. A central giant cell granuloma in posterior part of maxilla"”A case report. International Journal of Surgery Case Reports. 2017;30:222-225.
Yamaguchi T, Dorfman D. Giant cell reparative granuloma: a comparative clinicopathologic study of lesions in gnathic and extragnathic sites. Int J Surg Pathol. 2001;9(3):189- 200
Kermer C, Millesi W, Watzke M. Local injection of corticosteroids for central giant cell granuloma. A case report, Int J Oral Maxillofac Surg. 1994;23:366-368.
Dickerman JD. Interferon and giant cell tumors, Pediatrics. 1994;103:1282-1283.
Hameed M, O"™Connell J, Rogers S. Management of an aggressive giant cell granuloma of the mandible with denosumab: a case report. British Journal of Oral and Maxillofacial Surgery. 2019;57(7):691-693.
Liu B, Yu S, Li. Multinucleated giant cells in various forms of giant cell containing lesions of the jaws express features of osteoclasts. Journal of Oral Pathology and Medicine. 2003;32(6):367-375.
Chuong R, Kaban L, Kozakewich H, Perez-Atayde A. Central giant cell lesions of the jaws: A clinicopathologic study. Journal of Oral and Maxillofacial Surgery. 1986;44(9):708-713.
Chrcanovic B, Gomes C, Gomez R. Peripheral giant cell granuloma: An updated analysis of 2824 cases reported in the literature. Journal of Oral Pathology & Medicine. 2018;47(5):454-459.
Tabrizi R, Fardisi S, Zamiri B, Amanpour S, Karagah T. Can calcitonin nasal spray reduce the risk of recurrence of central giant cell granuloma of the jaws? A double-blind clinical trial. International Journal of Oral and Maxillofacial Surgery. 2016;45(6):756-759
Carlos R, Sedano H.. Intralesional corticosteroids as an alternative treatment for central giant cell granuloma. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2002;93(2):161-166.
Stavropoulos F, Katz J. Central giant cell granulomas: a systematic review of the radiographic characteristics with the addition of 20 new cases. Dentomaxillofacial Radiology. 2002;31(4):213-217.
Naidu A, Malmquist M, Denham C, Schow. Management of Central Giant Cell Granuloma With Subcutaneous Denosumab Therapy. Journal of Oral and Maxillofacial Surgery. 2014;72(12):2469-2484.
Bredell M, Rordorf T, Kroiss S, Rücker M, Zweifel D, Rostetter C. Denosumab as a Treatment Alternative for Central Giant Cell Granuloma: A Long-Term Retrospective Cohort Study. Journal of Oral and Maxillofacial Surgery. 2018;76(4):775-784.
Mukaihara K, Suehara Y, Kohsaka S, Akaike K, Tanabe Y, Kubota D, Saito T. Protein Expression Profiling of Giant Cell Tumors of Bone Treated with Denosumab. 2016;11(2).
Schreuder W, vandenBerg H, Westermann A, Peacock Z, Lange J. Pharmacological and surgical therapy for the central giant cell granuloma: A long-term retrospective cohort study. Journal of Cranio-Maxillofacial Surgery. 2017;45(2):232-243.
Chen Y, Zhang J, Han Y, Troulis M, August M. Benign Pediatric Jaw Lesions at Massachusetts General Hospital Over 13 Years. Journal of Oral and Maxillofacial Surgery. 2020;78(7):1124-1135.
Angelini A, Pagliarini E, Belluzzi E, Cappellesso R, Ruggieri P. Giant cell reparative granuloma of the scapula: report of a case and literature review. Skeletal Radiol. 2019;48(8):1293-1298.
Atarbashi-Moghadam F, Atarbashi-Moghadam S, Namdari M, Shahrabi-Farahani S. Reactive oral lesions associated with dental implants. A systematic review. J Investig Clin Dent. 2018;9(4).
Gadicherla S, Smriti K, John E, Pentapati K-C, Bhagania M. Intra-lesional medicaments for the management of intra-osseous lesions of maxilla and mandible - systematic review. J Int Soc Prev Community Dent. 2020;10(1):36-45.